June 8, 2015

Motion Sickness Drug Options

Available over the counter options
Antihistamines – helps to treat motion sickness
dimenhydrinate -
diphenhydramine
chlorpheniramine 
meclizine – less sedating
cyclizine
Additional drugs
Anticholinergics – helps to prevent motion sickness
Scopolamine - transdermal patch applied every 72 hours
Antidopaminergics 
Promethazine
Metoclopramide
Sympathomimetics 
Pseudoephedrine
Counseling points
·         Antihistamines also have anticholinergic side effects
o   sedation, blurred vision, mouth dryness
o   confusion and urinary retention in the elderly
·         Non-sedating antihistamines are not effective for motion sickness
·         Cognition - best to worst - meclizine, scopolamine, promethazine, lorazepam 
·         Pregnancy - antihistamines (meclizine, diphenhydramine, and dimenhydrinate), and prochlorperazine, are category C
·         If traveling – sit in front seat facing forward, look out the window, and not read a book or watch a movie
·         Avoid rapid changes in position and rapid head motion
·         Decrease use of products that impair circulation, e.g., tobacco, alcohol, caffeine, and salt
·         Get enough fluids
·         Treat infections, including ear infections, colds, flu, sinus congestion, and other respiratory infections
·         Avoid strong odors and spicy or greasy foods immediately before and during your travel
·         Talk to your doctor about medications

Contraindications
·         Asthma
·         glaucoma
·         urine retention

Call 911 or go to an emergency room if you experience:
·         Dizziness after a head injury
·         Fever over 101°F, headache, or very stiff neck
·         Convulsions or ongoing vomiting
·         Chest pain
·         Heart palpitations
·         Shortness of breath
·         Weakness
·         Severe headache
·         Inability to move an arm or leg
·         Change in vision or speech
·         Fainting and/or loss of consciousness
Emily W. Lankau. Motion Sickness. Available at: http://wwwnc.cdc.gov/travel/yellowbook/2014/chapter-2-the-pre-travel-consultation/motion-sickness