Question –
Patient receives a prescription for Lamisil (terbinafine) 250mg for 10days and
is inquiring when he may be allowed to drink alcohol again as he plans to
attend a wedding on day 11.
Answer – Lamasil
has a half-life of 22 to 26 hours with the half-life of 200 to 400 hours
from skin and adipose tissue. Half-life is the amount of time needed to
decrease the amount of drug in the body 50%. It usually takes 5 half-lives for
the drug to be eliminated from the body close to 100%. With a half-life of 24
hours it would take approximately 5 days for terbinafine to be eliminated from
the body. It would be best to wait 5 days before consuming alcohol after
finishing the course of terbinafine. I called Novartis and they recommended not
drinking alcohol with this product and they said they could not make a
recommendation for after the patient stopped taking the medication.
Source:
Terbinafine
hydrochloride. DrugPoints Summary. Micromedex 2.0.
Truven Health Analytics, Inc. Greenwood Village, CO. Available at: http://www.micromedexsolutions.com.
Accessed June 16, 2015.